Half-Dose of Ephedra Product Shown to be Safe and Effective for
FL, 18 November 2002
Exhibit Less Appetite With No Side Effects
evidence of the safety and efficacy of a popular ephedra-based commercial
weight loss supplement, Xenadrine RFA-1, has been shown in a recent
four-week study of 24 healthy obese female volunteers -- 12 of whom
were given Xenadrine RFA-1, while the other half received a placebo.
All followed the same calorie-restricted diet and participated in
a four times weekly supervised exercise program.
given the supplement, in half the normal dosage, experienced "significant
weight loss and appetite reduction over the placebo group without
any negative impacts on the cardiovascular parameters measured,"
reports Douglas S. Kalman, MS, RD, FACN. Kalman, Director of the
Nutrition Division of Miami Research Associates, served as Chief
Clinical Investigator for the study, which was just presented at
the 85th Annual Conference of the American Dietetic Association.
The study was published in poster/abstract format in the Journal
of the American Dietetic Association.
wanted to scientifically determine the short term safety and efficacy
of this popular commercial weight loss supplement," says Kalman.
"The results surprised us. At half the dose recommended by the manufacturer
of Xenadrine RFA-1, our subjects still lost about three times the
amount of weight of those on placebo who followed the same diet
and exercise plan. We also examined the effects of Xenadrine RFA-1
on cardiovascular health, and found no significant effects on heart
rate, blood pressure or EKG. Within the confines of the study, Xenadrine
RFA-1 appears to be safe and effective."
cardiac conclusions of the Florida-based safety study appear to
contradict allegations by ephedra opponents.
all ephedra products are alike, Kalman relates. "Whereas Xenadrine
RFA-1 is made with natural, herbal ephedra, many brands contain
questionable synthetic, unstable compounds." Kalman urges people
to read ingredients, purchase ephedra products from trusted manufacturers,
and follow dosage directions, since consumers who take more capsules
than directed may face potential problems. Anyone who is considering
using any weight loss product should see their physician first to
ensure a clean bill of health.
is a derivative of the Chinese root Ma Huang, a natural stimulant
and a primary ingredient in Xenadrine RFA-1, a thermogenic, appetite-suppressing,
fat-burning diet product that increases metabolism. Since 1997,
Xenadrine RFA-1 has helped millions of Americans safely lose tons
of weight each year. In addition, Xenadrine RFA-1 has been the subject
of seven other product-specific clinical trials on humans. In each
of these clinical studies, Xenadrine RFA-1 has been shown to be
safe and effective for weight loss.
Technologies, based in Manasquan NJ, supplies and distributes pharmaceutical-grade
supplements, including Xenadrine. Since its inception in 1997, Cytodyne
has placed a strong emphasis on research. The company's expert research
and development team works closely with top researchers and uses
cutting edge data to develop its supplements. Today Cytodyne is
one of the industry's largest sponsors of independent clinical research
on dietary supplements at universities throughout the world.
Technologies, via PR Newswire.